: An overproduction of goblet and Paneth cells, which can disrupt normal gut function.
: An R package used for genome-wide association studies (GWAS) to analyze complex genetic traits. 21703.rar
: Novel agonists like SY-1425 (tamibarotene) are being developed to selectively inhibit the growth of tumor cells that rely on high RARα expression. 3. Cellular Reprogramming : An overproduction of goblet and Paneth cells,
Research published in PNAS suggests that expressing RARα (alongside other factors) can drastically speed up and improve the efficiency of reprogramming somatic cells into pluripotent stem cells. Summary of Key Research Tools Intestinal Health and Immunity
RARα is a "critical node" in the treatment of various cancers, particularly leukemia:
If you are looking to synthesize information on for an academic or helpful paper, here are the key functional areas currently being researched: 1. Intestinal Health and Immunity