Founded in 300 BCE by Seleucus I Nicator, one of Alexander the Great’s generals, Antioch on the Orontes (modern-day Antakya, Turkey) served as a vital hinge between the Mediterranean and the Far East. Often called the "Queen of the East," it rose to become the third-largest city in the Roman Empire, trailing only Rome and Alexandria in size and magnificence. Its strategic location on trade routes like the Silk Road fueled a cosmopolitan culture that profoundly shaped early Christian history and Hellenistic Judaism.

Introduction

Antioch holds a unique status in religious history as the place where followers of Jesus were first called "Christians" (Acts 11:26). Following the destruction of Jerusalem in 70 CE, it emerged as the primary hub of Christian influence in the East.

Under Roman rule beginning in 64 BCE, Antioch became the capital of the province of Syria. At its zenith, the city housed up to 500,000 residents and was renowned for its architectural splendor, including: