Athena Heart - [310]

: Contraindicated in patients with symptomatic heart failure or recent hospitalization for heart failure (NYHA Class IV or symptomatic Class II-III).

Stop other Class I or III antiarrhythmics (e.g., amiodarone, sotalol) before starting Multaq. Avoid strong (e.g., ketoconazole). ATHENA HEART [310]

The official FDA label outlines critical safety measures based on ATHENA data: : : Contraindicated in patients with symptomatic heart failure

The ATHENA trial was a landmark study that evaluated the efficacy of dronedarone in reducing cardiovascular hospitalizations or death. The official FDA label outlines critical safety measures

Patients with paroxysmal or persistent AF or AFL who are in sinus rhythm or who will be cardioverted.

Monitor closely if the patient is also taking warfarin, as dronedarone can increase warfarin exposure. 4. Patient Monitoring

: To determine if dronedarone could lower the risk of hospitalization due to cardiovascular events or death from any cause in patients with atrial fibrillation (AF) or atrial flutter (AFL).