C4zip «Fast – 2024»

Preparing the resin with a wetting solution (e.g., 50:50 acetonitrile in water).

Allows for desalting and concentrating samples in a single, fast step. Standard Workflow for Sample Prep Preparing the resin with a wetting solution (e

Produced by Millipore , C4 Zip-tips are 10 µL pipette tips containing a specialized C4 (butyl) stationary phase resin. Unlike the more common C18 tips used for peptides, the C4 resin is optimized for larger, more hydrophobic molecules like intact proteins and large polypeptides. Why C4 over C18? Preparing the resin with a wetting solution (e

Using a high-organic solvent to release the purified protein directly onto a MALDI plate or into a fresh tube. Real-World Application: Mass Spectrometry Preparing the resin with a wetting solution (e

Aspirating and dispensing the protein sample multiple times to maximize binding.