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Their last meeting in Week 15 of the 2024 season was a high-scoring thriller that highlighted the parity between these cross-conference foes. Mon, Dec 16 Bills won!
The Bills historically hold the upper hand in this series, which began in 1972. The Bills lead 8-4-1. NFL Buffalo Bills vs Detroit Lions
How Lions and Bills match up ahead of game of the season - ESPN Their last meeting in Week 15 of the
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