Reactions Of Substituted Quinones | Fast

Substituted quinones are some of the most versatile electrophiles in organic chemistry. Because the quinone core is electron-deficient, their reactivity is largely governed by the nature and position of the substituents ( -groups) attached to the ring. 1. Nucleophilic Conjugate Addition (Michael Addition)

Large groups can hinder the approach of the diene, often dictating which face of the quinone is attacked. reactions of substituted quinones

If the quinone is unsymmetrically substituted, the nucleophile typically attacks the less hindered carbon or the carbon with the lowest electron density. Substituted quinones are some of the most versatile

) on the quinone accelerate the reaction by lowering the LUMO energy. reactions of substituted quinones