Transgender people are often among the strongest allies to lesbian, gay, and bisexual individuals, as both groups share a core goal of achieving autonomy and self-determination.

Transgender adults are twice as likely as cisgender adults to be uninsured. Economic vulnerability is also high; for example, the unemployment rate for transgender people is three times higher than the general population, with even higher disparities for people of color.

Transgender women of color, such as Marsha P. Johnson and Sylvia Rivera, were pivotal figures in the 1969 Stonewall Uprising , which is often credited as the catalyst for the modern LGBTQ rights movement.

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